Our projects aim to understand the regulatory mechanisms of inflammation and to develop immunotherapeutic strategies (new molecules or cell subpopulations) to control inflammatory responses in different pathological contexts.
Our projects aim to define therapeutic targets, characterise tumour-specific lymphocyte populations and develop immunotherapeutic strategies (vaccination or adoptive transfer of T cells) to combat solid tumours.
Our projects aim to characterise the innate and adaptive responses to infection by a pathogen or virus with the aim of developing immunotherapeutic strategies (molecules or adoptive transfer of T cells) to combat infections.
Immunology and New Concepts in Immunotherapy
Created in 2022, the INCIT(Immunology and New Concepts in Immunotherapy) research unit, directed by Frédéric Altare, is based on the desire to focus thescientific expertise of the immunology and immunotherapy teams on different pathological contexts: inflammation, cancer and infectious diseases.
Publications since 2016
Doctoral students and post-docs
Locations - Nantes and Angers
Teams of specialists
INCIT brings together a wide range of immunology skills among its 4 teams, with a common objective:
To decipher the cellular and molecular mechanisms associated with immune responses to develop immunotherapeutic strategies.
Modulation of immune and inflammatory responses.
Anti-tumor immunosurveillance and immunotherapy.
"Reactivation of the STING pathway to improve the efficacy of immunotherapies (anti-PD(L)1) in heterotypic spheroid models of urothelial carcinoma."
Dr Céline Gongora (Institut de cancérologie de Montpellier (IRCM), guest of Team 3, will give a seminar entitled: Reactivation of the STING pathway to improve the efficacy of immunotherapies (anti-PD-(L)1) in urothelial carcinoma models , June 21 at 11.00 - Rooms 1, 2, 3 - IRS2, Nantes
Catherine Rabu (team 3) will present her HDR entitled: Antigènes de tumeurs issus de LongNonCoding RNA: identification, modes d'expression et utilisation thérapeutique on June 16 at 14.30, rooms 1, 2, 3 at IRS2, Nantes.
Dr. Etienne Meunier (Institute of Pharmacology & Structural Biology (IPBS) will give a seminar entitled: Emerging innate immune sensors in microbial detection, on June 12 at 2:00 pm - Rooms 1, 2, 3 - IRS2, Nantes