This year, we are celebrating four years of unity. Thank you for being part of the adventure! 🎉

Research projects in Immuno-Inflammation

Our projects aim to understand the regulatory mechanisms of inflammation and to develop immunotherapeutic strategies (new molecules or cell subpopulations) to control inflammatory responses in different pathological contexts.

Research projects in Immuno-Cancerology

Our projects aim to define therapeutic targets, characterise tumour-specific lymphocyte populations and develop immunotherapeutic strategies (vaccination or adoptive transfer of T cells) to combat solid tumours.

Research projects in Immuno-Infectious Diseases

Our projects aim to characterise the innate and adaptive responses to infection by a pathogen or virus with the aim of developing immunotherapeutic strategies (molecules or adoptive transfer of T cells) to combat infections.

Immunology and New Concepts in Immunotherapy

About us

Created in 2022, the INCIT(Immunology and New Concepts in Immunotherapy) research unit, directed by Frédéric Altare, is based on the desire to focus thescientific expertise of the immunology and immunotherapy teams on different pathological contexts: inflammation, cancer and infectious diseases.

Workforce

Publications since 2016

Doctoral students and post-docs

Locations - Nantes and Angers

Teams of specialists

INCIT brings together a wide range of immunology skills among its 4 teams, with a common objective:

To decipher the cellular and molecular mechanisms associated with immune responses to develop immunotherapeutic strategies.

Incit Team 1

Team 1

Modulation of immune and inflammatory responses.

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Incit Equipe 3<br />

Team 3

Anti-tumor immunosurveillance and immunotherapy.

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Incit Equipe 2<br />

Team 2

Clinical and translational research in proliferative and inflammatory skin diseases.

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Incit Equipe 4<br />

Team 4

Pathophysiology and immune responses to M. Ulcerans.

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Our news

New Funding for F. Pecorari: ANR HYPERBAUM

New Funding for F. Pecorari: ANR HYPERBAUM

HYPERBAUM is one of the projects selected by the ANR as part of the 2026 call for proposals. The project aims to develop new therapeutic strategies or molecular targeting approaches against Acinetobacter baumannii, an opportunistic pathogen that is highly resistant to traditional antibiotics and classified as a critical priority by the World Health Organization (WHO).

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New Funding for F. Pecorari: ANR HYPERBAUM

New Funding for F. Pecorari: ANR HYPERBAUM

HYPERBAUM is one of the projects selected by the ANR as part of the 2026 call for proposals. The project aims to develop new therapeutic strategies or molecular targeting approaches against Acinetobacter baumannii, an opportunistic pathogen that is highly resistant to traditional antibiotics and classified as a critical priority by the World Health Organization (WHO).

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“Mathilde Deiber’s Thesis Defense: Modulation of Interactions Between Epithelial Cells and T Cells in Intestinal Pathology: Implications of the NLRC5/MHC-I Pathway and a Population of Regulatory T Cells (DP8α)”

“Mathilde Deiber’s Thesis Defense: Modulation of Interactions Between Epithelial Cells and T Cells in Intestinal Pathology: Implications of the NLRC5/MHC-I Pathway and a Population of Regulatory T Cells (DP8α)”

The entire INCIT Unit extends its warmest congratulations to Mathilde on her thesis defense, which focused on
the modulation of interactions between epithelial cells and T cells in intestinal diseases, with a particular focus on the NLRC5/MHC-I pathway and DP8α regulatory T cells.

A big thank you to the members of the jury: Marie-Cécile Michallet and Frédérick Barreau (rapporteurs), Céline Gongora and Guillaume Sarrabayrouse (examiners), and Emmanuel Scotet (chair of the jury).

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